Product Name

• Panadol Cold And Flu, Relieves Common Colds Symptoms – 24 Caplets

Scientific Name

• Paracetamol 500 Mg + Chlorpheniramine 2 Mg + Pseudoephedrine Hydrochloride 30 Mg Caplets

Category Of Panadol Cold And Flu Caplets

• Allergy & Cold Drugs

Mechanism Of Action Of Paracetamol, Chlorpheniramine & Pseudoephedrine

• Paracetamol acts on the hypothalamus to produce an antipyretic effect, as fever develops when the hypothalamus is set to a higher-than-normal temperature.
• Paracetamol may work peripherally to block pain impulse generation; may also inhibit prostaglandin synthesis in CNS
• H1 histamine receptor antagonist; competes for H1-receptor sites in target cells in the respiratory tract, blood vessels, and gastrointestinal tract.
• Chlorpheniramine is a sedative first-generation antihistamine
• Pseudoephedrine is a sympathomimetic with a mixed mechanism of action, direct and indirect.
• Pseudoephedrine is a decongestant used for reducing nasal congestion caused by allergies or the common cold.
• Pseudoephedrine causes blood vessels in the nasal passages to shrink (vasoconstrictor).
• Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into nasal passages.

Therapeutic Indications Of Panadol Cold And Flu Caplets

• It is used for the relief of the following indications:

1. Headache
2. Congestion and sinus pain
3. Sneezing
4. Body aches
5. Itchy and watery eyes
6. Blocked and runny nose
7. Fever
8. Relief from cold and flu symptoms.

Method Of Administration Of Panadol Cold And Flu Caplets

• Always take this medicine exactly as your doctor or pharmacist has told you.
• Check with your doctor or pharmacist if you are not sure.
• Shake well before uses
• The average doses: 1 tablets 3 – 4 times daily or as directed by a physician.
• Doses may be changed in special conditions so always follow your doctor’s or pharmacist’s instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Panadol Cold And Flu Caplets

• Although the following side effects are not common in everyone, some patients may complain from:

1. Headache
2. Minor nosebleeds (epistaxis) if used for over 6 weeks
3. Nasal ulceration
4. Pain in the throat
5. Shortness of breath
6. Pain, burning, irritation, soreness, or dryness on the inside of the nose