Product Name

• Fludrex, Relieves Common Colds Symptoms – 24 Tablets

Scientific Name

• Paracetamol 400 Mg + Chlorpheniramine Maleate 3Mg + Pseudoephedrine Hydrochloride + Caffeine 32 Mg Tablets

Category Of Fludrex Tablets

• Allergy & Cold Drugs

Mechanism Of Action Of Paracetamol, Chlorpheniramine, Pseudoephedrine & Caffeine

• Paracetamol acts on the hypothalamus to produce an antipyretic effect, as fever develops when the hypothalamus is set to a higher-than-normal temperature.
• Paracetamol may work peripherally to block pain impulse generation; may also inhibit prostaglandin synthesis in CNS
• H1 histamine receptor antagonist; competes for H1-receptor sites in target cells in the respiratory tract, blood vessels, and gastrointestinal tract.
• Chlorpheniramine is a sedative first-generation antihistamine
• Pseudoephedrine is a sympathomimetic with a mixed mechanism of action, direct and indirect.
• Pseudoephedrine is a decongestant used for reducing nasal congestion caused by allergies or the common cold.
• Pseudoephedrine causes blood vessels in the nasal passages to shrink (vasoconstrictor).
• Vasoconstriction reduces nasal congestion by preventing fluid from draining from blood vessels into nasal passages.
• Caffeine acts as a central nervous system (CNS) stimulant, people usually take it to feel more alert and energetic.
• Caffeine can improve mood and help people feel more productive. It is believed to work by blocking the neurotransmitter adenosine’s receptors, increasing excitability in the brain.

Therapeutic Indications Of Fludrex Tablets

• It is used for the relief of the following indications:

1. Headache
2. Congestion and sinus pain
3. Sneezing
4. Body aches
5. Itchy and watery eyes
6. Blocked and runny nose
7. Fever
8. Relief from cold and flu symptoms.

Method Of Administration Of Fludrex Tablets

• Always take this medicine exactly as your doctor or pharmacist has told you.
• Check with your doctor or pharmacist if you are not sure.
• Shake well before uses
• The average doses: 1 tablets 3 – 4 times daily or as directed by a physician.
• Doses may be changed in special conditions so always follow your doctor’s or pharmacist’s instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.